Cruis'n USA is an arcade racing game originally released in 1994. It was developed by Eugene Jarvis' company TV Games Inc., and manufactured by Midway Games. It is the first game in the Cruis'n series and features races set in locations across the continental United States.

Cruis'n USA is branded as the first release of the "Ultra 64" platform collaboration between Midway and Nintendo, although it was based on the Midway V-unit arcade hardware, predating the Killer Instinct arcade hardware which would become the Nintendo 64. The home port was published by Nintendo as part of the deal.

The arcade version was critically and commercially successful, drawing favorable comparisons to Sega's Daytona USA. The Nintendo 64 version received poor reviews, but was also commercially successful. It was released on Wii's Virtual Console in Europe on March 28, 2008, making it the first third party developed Nintendo 64 game to be released on the service. It became available on the Virtual Console in North America on March 31, 2008.